Introduction: Retinal capillary nonperfusion (CNP) is one of the retinal vascular diseases in diabetic retinopathy (DR) patients. As there is no comprehensive detection technique to recognize CNP areas. we proposed a different method for computing detection of ischemic retina. non-perfused (NP) regions. https://www.roneverhart.com/Cyspera-Pigment-Corrector-1-75oz-52ml/